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Scientist who developed India’s first indigenous vaccine dies at the age of 72.

Dr. M.K. Bhan addressing a Press Conference to apprise on the two significant R&D results emanating from DBT support, in New Delhi on May 31, 2012. The scientist who developed India’s first indigenous vaccine dies at 72. He was born in 1947, the year when India got independence and he passes away on 26th January, when India was celebrating its 71st Republic day. He was destined to be part of the country’s history. Maharaj Kishan Bhan is an Indian pediatrician and clinical scientist who developed the vaccine for rotavirus, the first indigenous vaccine produced in the country. He was born on 9th November 1947. He completed his MBBS degree from AFMC, Pune and M.D. Degree from Post Graduate Institute of Medical Education and Research, Chandigarh. As a faculty in AIIMS, Delhi he worked extensively on childhood diarrhea and nutrition. Childhood diarrhea is ...

Biodegradable burial pod turns your body into a tree.

Bretzel and Citelli with Capsula Mundi Model. Whenever a person dies, it is a burden for the family emotionally and financially. We spend thousands of dollars in funerals paying for the casket, flowers, and monuments. Environmentally, those caskets and monuments left behind an enormous carbon footprint. Recently, many people have begun to embrace the idea of green burials. People are environmentally more aware and there is a shift from cremation and the use of wood, the synthetic cushioning and the metals generally used in traditional coffins to green burial. Green burial is a method of burying the body in a wooden coffin without a concrete burial vault. The body along with the wooden coffin is degraded easily by the bacteria in the soil. This type of burial allows the graveyard to return to nature. Nearly 54 percent of Americans are considering green burial and 74 percent of cemeteries are reporting an increased demand for g...

Top 10 most revolutionary Nature articles of all time.

Template from Watson and Crick molecular Model, 1953 . Nature is one of the most recognizable and most cited scientific journals of the world with an impact factor of 43 (2018). Nature is edited and published in the United Kingdom by a scientific publishing company Springer Nature. Nature is a weekly journal. Being published in nature is very prestigious. Recently, on 04 November 2019, Nature published the top 10 most influential nature papers of all time. Here is the list with no particular order. The structure of DNA: On 25 th April 1953, James Watson and Francis Crick announced in Nature that they had elucidated the structure of DNA. In the early 1950s, the identity of genetic material was still a matter of debate. This discovery of the helical structure of double-stranded DNA settled the matter and change the history of biology forever. The advent and rise of monoclonal antibodies: In 1975, Georges Kohler and Cesar Milstein first report how cell ...

Vaginal Microbiome Transplantation (VMT) shows promises against Bacterial Vaginosis.

What is Bacterial vaginosis? Normally, Lactobacillus species dominated the microbiome community of human Vagina. Bacterial vaginosis is a vaginal inflammation. It occurs when there is disbalance in the bacterial community i.e. when anaerobes dominate the microbiome instead of Lactobacillus species. Symptoms of BV: Bacterial vaginosis (BV) is prevalent in women of reproductive age affecting from one-fourth to one-third of women. BV may be associated with the risk of upper genital tract infection, complications of pregnancy and susceptibility to sexually transmitted infections (STDs). The study: In this study, five patients suffering from Bacterial vaginosis were recruited . A healthy vaginal fluid for transplantation was collected from the donors . They were then transferred to the patients suffering from BV. All the patients were monitored...

Researchers from USA and Germany developed stem cells that could evade immune attack.

Researchers from the USA in collaboration with some German scientists have developed stem cells that can evade immune attack of the host. They used CRISPR-Cas9 technology to develop the cells. MHC complex defines whether the cells are your own or foreign. During organ transplantation, MHC of the donor and the recipient should be matched. If there is a mismatch between the two individuals in their MHC, the immune cells of the recipient considers the transplanted organ as foreign and will be destroyed by immune cells. No two individuals have identical MHC complexes. Normally foreign cells are attacked by immune cells. This is the main reason for the difficulty in transplantation. Using CRISPR, the researcher has deleted the genes that code for MHC complex and as a result, there is no more MHC in the cells. Since there is no more MHC, they are not recognized as foreign and are accepted as their own. One problem is that those cells that have no MHC are the target of another cell...

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