Template from Watson and Crick molecular Model, 1953. |
Nature is one of the most recognizable and most cited
scientific journals of the world with an impact factor of 43 (2018). Nature is
edited and published in the United Kingdom by a scientific publishing company
Springer Nature. Nature is a weekly journal. Being published in nature is very
prestigious.
Recently, on 04 November 2019, Nature published the top 10
most influential nature papers of all time. Here is the list with no particular
order.
The structure of DNA:
On 25th April 1953, James Watson
and Francis Crick announced in Nature that they had elucidated the structure of
DNA. In the early 1950s, the identity of
genetic material was still a matter of debate. This discovery of the helical structure
of double-stranded DNA settled the matter and change the history of biology forever.
The advent and rise of monoclonal
antibodies:
In 1975, Georges Kohler and Cesar Milstein
first report how cell lines could be made to produce an antibody of known
specificity.
Cell
identity reprogrammed:
In the 1940s, people believe that the
differentiation of cells is irreversible. However, in 1950s , Gurdon and
colleagues concluded through their research that Developmental clock can be This
laid the foundation of modern methods of reprogramming cell identity and
promising new regenerative therapies.
Australopithecus provided insight
into human evolution
In 1925, Raymond Dart published a report of
an African fossil of a previously unknown genus Australopithecus. This the finding helps us understand how humans evolved after its split with apes
in the evolutionary tree.
Discovery of Antarctic Ozone hole:
In 1985, Joe Farman and colleagues reported
that the stratospheric ozone layer was only about two-thirds as thick as seen
in earlier decades. The phenomenon became known as the Antarctic ozone hole.
This discovery helped established one of the most successful global environmental
policies of the twentieth century.
Discovery of patch-clamp techniques:
Initially, it was developed to record currents
of ions flowing through channel proteins in the membranes of cells. The patch-clamp technique has become a true stalwart of the neuroscience toolbox.
Discovery of C60:
In 1985, scientists reported the discovery
of cage-like carbon molecule C60. It paves the way for materials
such as graphene and carbon nanotube and was a landmark in the emergence of
nanotechnology.
Birth of class of nanomaterial :
In 1992, Kresge et el report a breakthrough
in material science, a material that is regularly arranged with mesoscopic
diameters (between 2 and 50 nanometres).
Detection of strange particles:
In 1947, scientists first reported an
unseen particle which is now called neutral kaon. This work led to the
establishment of elementary particles known as quarks.
The first exoplanet found around a sun-like
star:
In 1995, astronomers detected a blistering
hot Jupiter mass planet orbiting closer to its hot star than the mercury is to
the sun. This discovery recast our thinking of how planets form and let to a a new era of exoplanetary exploration.
References:
Nature,( 2019)
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